Intraepithelial carcinoma (Bowen disease)
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ກໍລະນີທົ່ວໄປ - Intraepithelial carcinoma (Bowen disease) ອາດຈະຖືກວິນິເສດຜິດເປັນ eczema ດັ່ງນັ້ນ, ບໍ່ມີອາການຄັນ.
relevance score : -100.0%
ReferencesBowen's disease (BD) ເປັນມະເຮັງຜິວໜັງຊະນິດໜຶ່ງທີ່ເລີ່ມຢູ່ໃນຊັ້ນນອກຂອງຜິວໜັງ (epidermis). ມັນພົບເລື້ອຍໃນຊາວ Caucasians ແລະມັກຈະເກີດຂື້ນໃນບ່ອນທີ່ເຂົາເຈັດສະແດງແດດ, ແຕ່ກໍ່ສາມາດປາກົດໄດ້ທີ່ບ່ອນອື່ນເຊັ່ນກັນ. BD ປົກກະຕິແລ້ວສະແດງໃຫ້ເຫັນວ່າເປັນ lesion ດຽວ. BD ມັກຈະເປັນສັນຍານເຕືອນກ່ອນທີ່ຈະພັດທະນາເປັນມະເຮັງຜິວໜັງຊະນິດຮ້າຍແຮງ. ເພື່ອວິນິດໄສ BD, ທ່ານໝໍມັກຈະອີງໃສ່ການກວດຕົວຢ່າງເນື້ອເຍື່ອພາຍໃຕ່ກ້ອງຈຸລະທັດ (biopsy).
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen’s disease ( ສ່ວນຫຼາຍແມ່ນມີຜົນກະທົບກັບຄົນຜິວຂາວທີ່ມີອາຍຸຫຼາຍກວ່າ 60 ປີ). ພະຍາດມີອຸບາຍສັງຄົມທີ່ສາມາດເກີດຂຶ້ນໃນໄລຍະຍາວ, ລະບົບພູມຄຸ່ມກັນອ່ອນ, ການຕິດເຊື່ອງອາເຊນິກ, ແລະການຕິດເຊື່ອງ HPV ���ິວຫນັງ. ໂຊ່ສັບ HPV ຊະນິດ 16, 18, 34, ແລະ 48 ມີການສະໜັບສະໜູນກັບ Bowen’s disease ໃນການພັດທະນາອັດຕະພາບ. ການມີສ່ວນຮ່ວມຂອງ HPV ໃນກໍລະນີທີ່ບໍ່ແມ່ນອັດຕະພາບມີຄວາມຊັດເຈນຕໍ່ການພັດພາດຕໍ່ໄປ.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
ມັນມັກຈະປາກົດເປັນບໍລິເວນທີ່ມີການເກັດຕໍ່ກັນ, ເປັນກ່ອນກັນ ຫຼື ເກັດຕໍ່ກັນຢູ່ທົ່ວຮ່າງ. ສະຖານທີ່ພົບບໍ່ສະຫນັບສະໜຸນທີ່ສຸດແມ່ນຂາຕ່ຳ.
ມັນສາມາດຖັດການປິ່ນປົວໂດຍວິທີຕ່າງໆ ເຊັ່ນ: ການປິ່ນປົວດ້ວຍ cryotherapy, curettage, cautery, photodynamic therapy ຫຼື excision ຂອງ lesion.
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